Bipolar Disorder Due to Another Medical Condition

Evidence-based mental health content, reviewed by psychologists and psychiatrists

Bipolar Disorder Due to Another Medical Condition

Medically reviewed · Ratel Health editorial team · Sunday, 16 August 2026

A condition involving a prominent, persistent disturbance in mood characterized by elevated or irritable mood, judged to be the direct physiological result of a medical condition.

Overview

Bipolar disorder due to another medical condition involves a prominent and persistent period of abnormally elevated or irritable mood, with or without depressive symptoms, judged to be the direct physiological consequence of an underlying medical condition, such as thyroid disease or certain neurological conditions.

Signs and Symptoms

Symptoms can include elevated, expansive, or irritable mood, increased energy, and decreased need for sleep, occurring in close relationship to the underlying medical condition. Experiencing one or more of these symptoms does not necessarily mean that a person has this condition. Diagnosis requires an appropriate clinical evaluation.

Causes and Risk Factors

This condition can result from conditions such as thyroid disorders, certain neurological conditions, or other medical illnesses that directly affect brain function regulating mood.

Diagnosis

A diagnosis should be made by a qualified healthcare professional following a comprehensive clinical assessment. Clinicians may use established diagnostic frameworks such as DSM-5-TR and/or ICD-11 as part of a comprehensive assessment.

Treatment

Treatment depends on the individual’s symptoms, clinical history, severity, age, co-occurring conditions, and other relevant factors.

Psychotherapy

Treatment of the underlying medical condition is central, alongside psychiatric symptom management.

Medication

Mood-stabilizing or antipsychotic medication may be used to manage acute symptoms while the underlying medical condition is treated. Medication decisions should be made with a qualified prescribing healthcare professional. Do not start, stop, or change a prescribed medication based solely on information on this page.

Living With Bipolar Disorder Due to Another Medical Condition

Identifying and treating the underlying medical cause is essential, alongside psychiatric symptom monitoring.

When to Seek Professional Help

Professional evaluation may be appropriate if symptoms persist, worsen, cause significant distress, or interfere with work, school, or relationships.

Emergency Situations

If a person may be in immediate danger, is experiencing a medical or psychiatric emergency, or may harm themselves or another person, seek immediate assistance through appropriate local emergency services.

Outlook

Outcomes depend substantially on successful identification and treatment of the underlying medical condition.

Related Conditions

Medical Information Disclaimer

Ratel Health provides general educational information and does not provide medical diagnosis, treatment, or individualized medical advice. Information on this page is not a substitute for evaluation or care from a qualified healthcare professional. Do not use this information to diagnose yourself or another person, or to start, stop, or change treatment or medication without consulting an appropriately qualified healthcare professional.

References

  • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR).
  • National Institute of Mental Health.
  • U.S. Food and Drug Administration.
  • World Health Organization. International Classification of Diseases, 11th Revision.