Phencyclidine (PCP) Use Disorder

Evidence-based mental health content, reviewed by psychologists and psychiatrists

Phencyclidine (PCP) Use Disorder

Medically reviewed · Ratel Health editorial team · Sunday, 16 August 2026

A substance use disorder involving a problematic pattern of phencyclidine (PCP) or related dissociative substance use leading to clinically significant impairment or distress.

Overview

Phencyclidine use disorder involves a problematic pattern of use of PCP or related dissociative substances leading to clinically significant impairment or distress, including strong cravings and continued use despite serious risks.

Signs and Symptoms

Symptoms can include using more than intended, strong cravings, and continued use despite psychological, physical, or legal problems caused by the substance. Experiencing one or more of these symptoms does not necessarily mean that a person has this condition. Diagnosis requires an appropriate clinical evaluation.

Causes and Risk Factors

Risk factors include social and environmental exposure, co-occurring mental health conditions, and prior substance use history.

Diagnosis

A diagnosis should be made by a qualified healthcare professional following a comprehensive clinical assessment. Clinicians may use established diagnostic frameworks such as DSM-5-TR and/or ICD-11 as part of a comprehensive assessment.

Treatment

Treatment depends on the individual’s symptoms, clinical history, severity, age, co-occurring conditions, and other relevant factors.

Psychotherapy

Behavioral therapies, including cognitive behavioral therapy, may help address problematic use.

Living With Phencyclidine (PCP) Use Disorder

PCP use carries risk of severe agitation, injury, and dangerous behavior; seeking prompt medical support during acute intoxication is important.

When to Seek Professional Help

Professional evaluation may be appropriate if symptoms persist, worsen, cause significant distress, or interfere with work, school, or relationships.

Emergency Situations

If a person may be in immediate danger, is experiencing a medical or psychiatric emergency, or may harm themselves or another person, seek immediate assistance through appropriate local emergency services.

Outlook

Outcomes vary; many individuals improve with structured behavioral treatment and social support.

Related Conditions

Medical Information Disclaimer

Ratel Health provides general educational information and does not provide medical diagnosis, treatment, or individualized medical advice. Information on this page is not a substitute for evaluation or care from a qualified healthcare professional. Do not use this information to diagnose yourself or another person, or to start, stop, or change treatment or medication without consulting an appropriately qualified healthcare professional.

References

  • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR).
  • National Institute of Mental Health.
  • U.S. Food and Drug Administration.
  • World Health Organization. International Classification of Diseases, 11th Revision.