Serotonin Syndrome

Overview Serotonin syndrome is a potentially serious condition resulting from excess serotonergic activity in the nervous system, typically caused by combining two or more serotonin-affecting medications or substances, ranging from mild to life-threatening in severity. Signs and Symptoms Symptoms can include agitation, confusion, rapid heart rate, high blood pressure, dilated pupils, muscle twitching, tremor, sweating, …

Medication-Induced Acute Akathisia

Overview Medication-induced acute akathisia involves subjective complaints of restlessness, often accompanied by observed excessive movement such as fidgeting or pacing, developing within days to weeks of starting or increasing certain medications, most commonly antipsychotics. Signs and Symptoms Symptoms can include an intense, uncomfortable urge to move, inability to sit still, pacing, and significant distress, which …

Neuroleptic Malignant Syndrome

Overview Neuroleptic malignant syndrome is a rare but potentially life-threatening condition that can occur after exposure to antipsychotic or other dopamine-blocking medications, involving severe muscle rigidity, high fever, altered mental status, and autonomic instability. Signs and Symptoms Symptoms can include severe muscle stiffness, high fever, confusion, rapid heart rate, and unstable blood pressure, typically developing …

Tardive Dyskinesia

Overview Tardive dyskinesia is a movement disorder involving involuntary, repetitive movements, most commonly affecting the face, tongue, or limbs, that can develop after prolonged exposure to certain antipsychotic or other dopamine-blocking medications. Signs and Symptoms Symptoms can include repetitive movements such as lip-smacking, tongue movements, grimacing, or involuntary limb movements, which can be socially distressing …

Burnout

Overview Burnout, as recognized by the World Health Organization in the ICD-11, is an occupational phenomenon resulting from chronic workplace stress that has not been successfully managed, characterized by feelings of energy depletion, increased mental distance from one’s job, and reduced professional efficacy. It is not classified as a medical condition. Signs and Symptoms Symptoms …

Non-Suicidal Self-Injury

Overview Non-suicidal self-injury involves deliberate, self-inflicted damage to the surface of the body, without suicidal intent, often occurring in response to intense negative emotions or as a way to relieve distress, on five or more days within a year. Signs and Symptoms Symptoms can include repeated self-injury (such as cutting or burning) in response to …

Suicidal Behavior Disorder

Overview Suicidal behavior disorder is a condition included for further study in the DSM-5, referring to a suicide attempt within the past 24 months, used to help direct clinical attention, risk assessment, and follow-up care. Signs and Symptoms This classification is based on the occurrence of a recent suicide attempt itself, rather than a specific …

Internet Gaming Disorder

Overview Internet gaming disorder involves persistent and recurrent gaming, often with other users, leading to clinically significant impairment or distress across multiple areas of functioning. Signs and Symptoms Symptoms can include preoccupation with gaming, withdrawal symptoms when gaming is taken away, loss of interest in previous hobbies, and continued excessive gaming despite awareness of negative …

Gender Dysphoria

Overview Gender dysphoria involves a marked incongruence between an individual’s experienced or expressed gender and their assigned gender at birth, lasting at least six months and associated with clinically significant distress or impairment. Signs and Symptoms Symptoms can include distress related to the mismatch between one’s gender identity and physical characteristics, a strong desire to …